Roman troops enter the 206 a. C., during the Second Punic War, under the command of General Scipio and end with the Carthaginians who lived and defended the region, and its successors in southern Spain. The general decided to set Italic (now in ruins) in the vicinity of a nearby hill and at the same time away, to prevent belligerents.
The Romans Latinized the indigenous name of the city ("Ispal") and called Hispalis, with the full official name "Colonia Iulia Romula Hispalis." Thus, Julius Caesar founded Híspalis, naming Julia by name and Romulus (Rome's Girl) by Rome.
Hispalis developed as a commercial center and largest industrial Hispania, while Italica consolidated as typical Roman residential town where they were born several emperors Trajan, Hadrian and, perhaps, Theodosius.
During this period was capital of a legal convents Baetica, the Seville. Italica Híspalis and ended up having each its particular feature: as a city Híspalis financial, commercial and industrial Hispano-Roman, and Italic as a residential town, genuinely Roman.
In the year 49 a. C., Híspalis had walls and forum. Considered as a replica of Rome, was one of the most important cities of Andalusia and Hispania. In the last centuries of the Empire was the eleventh of world.3 Hispalis was a city of great movement and an important commercial port activity.
A mid-second century A.D. There were a couple of attempts of invasion by the Moors (mauris), which were finally expelled by Roman archers.
Christianity came early to the city and in the third century the sisters were martyred Saints Justa and Rufina (about current patterns of the city), according to legend by refusing to worship Astarte.